Case Report

Acute kidney injury in an HIV patient with plasmablastic lymphoma – A double-edged sword

Gerhard van Wyk, Liezel Coetzee, Mogamat-Yazied Chothia
Southern African Journal of Infectious Diseases | Vol 39, No 1 | a637 | DOI: https://doi.org/10.4102/sajid.v39i1.637 | © 2024 Gerhard van Wyk, Liezel Coetzee, Mogamat-Yazied Chothia | This work is licensed under CC Attribution 4.0
Submitted: 13 March 2024 | Published: 31 May 2024

About the author(s)

Gerhard van Wyk, Department of Nephrology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
Liezel Coetzee, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
Mogamat-Yazied Chothia, Department of Nephrology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa

Abstract

HIV patients frequently develop acute kidney injury (AKI) because of sepsis and diarrhoeal disease. Here, we report a case of an HIV-positive man with partially treated sinonasal plasmablastic lymphoma (PBL) and unexplained AKI. A kidney biopsy revealed two pathological processes.

Contribution: While urinary tract obstruction is the most common mechanism by which PBL causes AKI, maintaining a high level of suspicion for multiple pathological processes in cases involving light chain producing PBL.

 


Keywords

acute kidney injury; light chains; cast nephropathy; HIV; tumour infiltration

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