Case Report

Disseminated fungal infection in an HIV-infected patient due to Aureobasidium pullulans

Wesley G. van Hougenhouck-Tulleken, Garrison Mathole, Alan Karstaedt, Nimmisha Govind, Magendhree Moodley, Sharona Seetharam, Nelesh P. Govender, Colin N. Menezes
Southern African Journal of Infectious Diseases | Vol 31, No 3 | a79 | DOI: https://doi.org/10.4102/sajid.v31i3.79 | © 2019 Wesley G. van Hougenhouck-Tulleken, Garrison Mathole, Alan Karstaedt, Nimmisha Govind, Magendhree Moodley, Sharona Seetharam, Nelesh P. Govender, Colin N. Menezes | This work is licensed under CC Attribution 4.0
Submitted: 15 May 2019 | Published: 01 October 2016

About the author(s)

Wesley G. van Hougenhouck-Tulleken, Division of Rheumatology, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Garrison Mathole, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Alan Karstaedt, Division of Infectious Diseases, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Nimmisha Govind, Division of Rheumatology, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Magendhree Moodley, Department of Clinical Microbiology and Infectious Diseases, National Health Laboratory Service, Johannesburg, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Sharona Seetharam, Department of Clinical Microbiology and Infectious Diseases, National Health Laboratory Service, Johannesburg, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Nelesh P. Govender, National Institute for Communicable Diseases(Centre for Opportunistic, Tropical and Hospital Infections), a division of the National Health Laboratory Service, Johannesburg, South Africa, South Africa
Colin N. Menezes, Division of Infectious Diseases, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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Abstract

In South Africa, novel fungal pathogens have emerged as an important cause of disease in HIV-infected individuals. The clinical presentation is characteristically prolonged, insidious and the diagnosis elusive, often being made post mortem. We report an HIV-infected individual with a systemic mycosis due to Aureobasidium pullulans, a ubiquitous dematiaceous mould which has not been described in HIV-infected individuals.

Keywords

Aureobasidium pullulans; disseminated fungal infection; HIV; immune suppression; septic arthritis; systemic mycosis

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