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Brief Report
Multisystem cytomegalovirus end-organ disease in a patient with advanced HIV
Southern African Journal of Infectious Diseases | Vol 37, No 1 | a468 |
DOI: https://doi.org/10.4102/sajid.v37i1.468
| © 2022 Ruan Spies, Pierre Joubert, Dharshnee Chetty, Sipho Dlamini, Muhammed S. Moosa
| This work is licensed under CC Attribution 4.0
Submitted: 10 July 2022 | Published: 11 November 2022
Submitted: 10 July 2022 | Published: 11 November 2022
About the author(s)
Ruan Spies, Department of Medicine, New Somerset Hospital, Cape Town, South AfricaPierre Joubert, Department of Medicine, New Somerset Hospital, Cape Town, South Africa
Dharshnee Chetty, Division of Anatomical Pathology, Department of Pathology, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa
Sipho Dlamini, Division of Infectious Diseases and HIV Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; and, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
Muhammed S. Moosa, Department of Medicine, New Somerset Hospital, Cape Town, South Africa; and, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
Abstract
Cytomegalovirus (CMV) infection is common in people living with HIV, but multisystem CMV end-organ disease (EOD) is rare following the introduction of effective antiretroviral therapy. We present the case of a patient with advanced HIV and multisystem manifestations of CMV EOD.
Contributions: This case report highlights the potential morbidity and mortality associated with CMV disease in patients with advanced HIV. Clinicians should be vigilant in considering CMV EOD in patients with advanced HIV and visual, neurological and gastointestinal symptoms.
Keywords
cytomegalovirus; AIDS; HIV; CMV; end-organ disease; opportunistic infection
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