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Brief Report
Descriptive analysis of infections due to New Delhi metallo-β-lactamase-producing Enterobacterales in children at Red Cross War Memorial Children’s Hospital
Southern African Journal of Infectious Diseases | Vol 37, No 1 | a440 |
DOI: https://doi.org/10.4102/sajid.v37i1.440
| © 2022 Leonore Greybe, James J.C. Nuttall, Adrian J. Brink, Hafsah D. Tootla
| This work is licensed under CC Attribution 4.0
Submitted: 19 April 2022 | Published: 27 July 2022
Submitted: 19 April 2022 | Published: 27 July 2022
About the author(s)
Leonore Greybe, Pediatric Infectious Diseases Unit, Red Cross War Memorial Children’s Hospital, Cape Town, South Africa; and, Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South AfricaJames J.C. Nuttall, Pediatric Infectious Diseases Unit, Red Cross War Memorial Children’s Hospital, Cape Town, South Africa; and, Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa
Adrian J. Brink, Microbiology Laboratory, National Health Laboratory Service, Groote Schuur Hospital and Red Cross War Memorial Children’s Hospital, Cape Town, South Africa; and, Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, South Africa
Hafsah D. Tootla, Microbiology Laboratory, National Health Laboratory Service, Groote Schuur Hospital and Red Cross War Memorial Children’s Hospital, Cape Town, South Africa; and, Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, South Africa
Abstract
The increased incidence and absence of antibiotic treatment options for New Delhi metallo-β-lactamase (NDM)-producing carbapenem-resistant Enterobacterales (CRE) infection are concerning. Recent reports have highlighted NDM-producing Serratia marcescens, as a specific concern, as it is an organism which is intrinsically resistant to colistin. In this study, a descriptive analysis of NDM-producing CRE infections was performed at the Red Cross War Memorial Children’s Hospital.
Keywords
paediatrics; Serratia marcescens; Enterobacterales; antibiotic resistance; carbapenem resistance; New Delhi metallo-β-lactamase; carbapenemases
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