Case Report

Disseminated mucormycosis presenting as a renal mass in an human immunodeficiency virus-infected patient: A case report

Moshawa C. Khaba, Lesedi M. Nevondo, Sydney M. Moroatshehla, Ndivhuho A. Makhado
Southern African Journal of Infectious Diseases | Vol 36, No 1 | a202 | DOI: https://doi.org/10.4102/sajid.v36i1.202 | © 2021 Moshawa C. Khaba, Lesedi M. Nevondo, Sydney M. Moroatshehla, Ndivhuho A. Makhado | This work is licensed under CC Attribution 4.0
Submitted: 30 March 2020 | Published: 02 March 2021

About the author(s)

Moshawa C. Khaba, Department of Anatomical Pathology, Faculty Health Sciences, National Health Laboratory Service, Sefako Makgatho Health Sciences University, Pretoria, South Africa
Lesedi M. Nevondo, Department of Anatomical Pathology, Faculty Health Sciences, Sefako Makgatho Health Sciences University, Pretoria, South Africa
Sydney M. Moroatshehla, Department of Urology, Faculty Health Sciences, Sefako Makgatho Health Sciences University, Pretoria, South Africa
Ndivhuho A. Makhado, Department of Microbiology, Faculty Health Sciences, Sefako Makgatho Health Sciences University, Pretoria, South Africa

Abstract

Mucormycosis, an opportunistic fungal infection, is on the increase. Individuals at risk are those with diabetes mellitus, haematological malignancy, etc. Infections are uncommon in human immunodeficiency virus (HIV). Clinical presentations include rhinocerebral, pulmonary or disseminated forms. Risk factors should alert clinicians to a high index of suspicion. Prompt diagnosis, facilitated by radiological imaging and tissue sampling, with appropriate medical and surgical intervention can potentially improve patient outcomes. Here we describe a rare case of renal mass in a patient living with HIV presenting to casualty department with abdominal pain and fever. Radiological imaging showed a renal mass whilst histopathological findings were suggestive of mucormycosis. Management included antifungal therapy and subsequent nephrectomy. The patient improved significantly and was discharged home.

Keywords

mucormycosis; disseminated; human immunodeficiency virus; AIDS; renal mass.

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Crossref Citations

1. Clinical presentations, diagnosis, management, and outcomes of renal mucormycosis: An overview of case reports
Mojtaba Didehdar, Zahra Chegini, Amin Khoshbayan, Alireza Moradabadi, Aref Shariati
Frontiers in Medicine  vol: 9  year: 2022  
doi: 10.3389/fmed.2022.983612