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Case Report
Colistin-Resistant Acinetobacter baumannii as a cause of Neonatal Ventriculitis
Southern African Journal of Infectious Diseases | Vol 33, No 5 | a141 |
DOI: https://doi.org/10.4102/sajid.v33i5.141
| © 2019 Prasha Mahabeer, Bongani Wiseman Mzimela, Radhika Singh, Melissa Ann Veronica Lawler, Ashika Singh Moodley, Koleka Mlisana
| This work is licensed under CC Attribution 4.0
Submitted: 30 May 2019 | Published: 04 September 2018
Submitted: 30 May 2019 | Published: 04 September 2018
About the author(s)
Prasha Mahabeer, Department of Microbiology, KwaZulu-Natal Academic Complex, National Health Laboratory Service, Durban, South AfricaBongani W. Mzimela, Department of Paediatrics and Child Health, University of KwaZulu-Natal, Durban, South Africa
Melissa A. Lawler, Department of Paediatrics and Child Health, University of KwaZulu-Natal, Durban, South Africa
Ashika Singh-Moodley, Centre for Health Care Associated Infections, Antimicrobial resistance and Mycoses, National Institute for Communicable Diseases, Johannesburg, South Africa
Radhika Singh, Department of Paediatrics and Child Health, University of KwaZulu-Natal, Durban, South Africa
Koleka P. Mlisana, Department of Microbiology, KwaZulu-Natal Academic Complex, National Health Laboratory Service, Durban, South Africa
Full Text:
PDF (654KB)Abstract
Acinetobacter baumannii causes invasive paediatric infections, including bacteraemia and meningitis, but neonatal meningitis and ventriculitis is uncommon. The treatment of multidrug resistant (MDR) Acinetobacter infections often relies on colistin, a polymyxin antibiotic, as a last resort. Increased use of this drug has led to the emergence of colistin resistance. An unusual case of colistin-resistant Acinetobacter baumannii ventriculitis in a premature neonate managed with intraventricular colistin is described.
Keywords
Acinetobacter baumanii; colistin; neonatal; ventriculitis
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1. Molecular characterisation of Acinetobacter baumannii isolates from bloodstream infections in a tertiary-level hospital in South Africa
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