Case Report

Colistin-Resistant Acinetobacter baumannii as a cause of Neonatal Ventriculitis

Prasha Mahabeer, Bongani W. Mzimela, Melissa A. Lawler, Ashika Singh-Moodley, Radhika Singh, Koleka P. Mlisana
Southern African Journal of Infectious Diseases | Vol 33, No 5 | a141 | DOI: https://doi.org/10.4102/sajid.v33i5.141 | © 2019 Prasha Mahabeer, Bongani Wiseman Mzimela, Radhika Singh, Melissa Ann Veronica Lawler, Ashika Singh Moodley, Koleka Mlisana | This work is licensed under CC Attribution 4.0
Submitted: 30 May 2019 | Published: 04 September 2018

About the author(s)

Prasha Mahabeer, Department of Microbiology, KwaZulu-Natal Academic Complex, National Health Laboratory Service, Durban, South Africa
Bongani W. Mzimela, Department of Paediatrics and Child Health, University of KwaZulu-Natal, Durban, South Africa
Melissa A. Lawler, Department of Paediatrics and Child Health, University of KwaZulu-Natal, Durban, South Africa
Ashika Singh-Moodley, Centre for Health Care Associated Infections, Antimicrobial resistance and Mycoses, National Institute for Communicable Diseases, Johannesburg, South Africa
Radhika Singh, Department of Paediatrics and Child Health, University of KwaZulu-Natal, Durban, South Africa
Koleka P. Mlisana, Department of Microbiology, KwaZulu-Natal Academic Complex, National Health Laboratory Service, Durban, South Africa

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Abstract

Acinetobacter baumannii causes invasive paediatric infections, including bacteraemia and meningitis, but neonatal meningitis and ventriculitis is uncommon. The treatment of multidrug resistant (MDR) Acinetobacter infections often relies on colistin, a polymyxin antibiotic, as a last resort. Increased use of this drug has led to the emergence of colistin resistance. An unusual case of colistin-resistant Acinetobacter baumannii ventriculitis in a premature neonate managed with intraventricular colistin is described.

Keywords

Acinetobacter baumanii; colistin; neonatal; ventriculitis

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