Case Report
Candida pericarditis and tamponade from a malignant pericardio-oesophageal fistula
Submitted: 01 May 2025 | Published: 31 August 2025
About the author(s)
Nicola K. Wills, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town Division of Pulmonology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South AfricaPriyadarshini Arnab, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
Ferninand Oompie, Division of Radiology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
Nectarios S. Papavarnavas, Division of Infectious Diseases and HIV Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
Abstract
We describe the case of a middle-aged man and long-term smoker, presenting in cardiac tamponade with paroxysmal atrial flutter, with translocation of Candida glabrata into the pericardial space as a result of an erosive malignant oesophago-pericardial fistula.
Contribution: The isolation of Candida species from the pericardial space is a rare manifestation of invasive candida infection, carrying a high mortality rate, and requires interrogation for possible underlying immune aberrations or mechanical portals of entry.
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