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Brief Report
The sting in the tail of severe falciparum malaria: Post-artesunate delayed haemolysis
Southern African Journal of Infectious Diseases | Vol 37, No 1 | a392 |
DOI: https://doi.org/10.4102/sajid.v37i1.392
| © 2022 Yael Benjamin, David Stead
| This work is licensed under CC Attribution 4.0
Submitted: 07 December 2021 | Published: 25 May 2022
Submitted: 07 December 2021 | Published: 25 May 2022
About the author(s)
Yael Benjamin, Department of Internal Medicine, Frere Hospital, East London, South AfricaDavid Stead, Department of Internal Medicine, Frere Hospital, East London, South Africa; and, Department of Medicine, Faculty of Health Sciences, Walter Sisulu University, Mthatha, South Africa
Abstract
Post-artesunate delayed haemolysis (PADH) is thought to occur because of delayed clearance of previously malarial infected erythrocytes spared by ‘pitting’ during treatment. We report a case of PADH following the treatment of Plasmodium (P.) falciparum malaria (32% parasitaemia), with a positive direct antiglobulin (DAT) test, suggesting an immune mechanism.
Keywords
malaria; zoonoses; protozoan infections; falciparum malaria; tropical diseases; haemolytic anaemia; autoimmune haemolytic anaemia
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