Guideline

Federation of Infectious Diseases Societies of Southern Africa guideline: Recommendations for the detection, management and prevention of healthcare-associated Candida auris colonisation and disease in South Africa

Nelesh P. Govender, Theunis Avenant, Adrian Brink, Vindana Chibabhai, Joy Cleghorn, Briette du Toit, Chetna Govind, Elsie Lewis, Warren Lowman, Hleziphi Mahlangu, Caroline Maslo, Angeliki Messina, Mervyn Mer, Kim Pieton, Sharona Seetharam, Charlotte Sriruttan, Karin Swart, Erika van Schalkwyk
Southern African Journal of Infectious Diseases | Vol 34, No 1 | a163 | DOI: https://doi.org/10.4102/sajid.v34i1.163 | © 2019 Nelesh P. Govender, Theunis Avenant, Adrian Brink, Vindana Chibabhai, Joy Cleghorn, Briette du Toit, Chetna Govind, Elsie Lewis, Warren Lowman, Hleziphi Mahlangu, Caroline Maslo, Angeliki Messina, Mervyn Mer, Kim Pieton, Sharona Seetharam, Charlotte Sriru | This work is licensed under CC Attribution 4.0
Submitted: 04 June 2019 | Published: 26 September 2019

About the author(s)

Nelesh P. Govender, National Institute for Communicable Diseases, Centre for Healthcare-Associated Infections, Antimicrobial Resistance and Mycoses, Division of the National Health Laboratory Service, Johannesburg, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; and Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
Theunis Avenant, Kalafong Provincial Tertiary Hospital and Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa
Adrian Brink, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; and Ampath Laboratories, Cape Town, South Africa
Vindana Chibabhai, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; National Health Laboratory Service, Johannesburg, South Africa; and Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa
Joy Cleghorn, Life Healthcare Group, Johannesburg, South Africa
Briette du Toit, Mediclinic Southern Africa, Cape Town, South Africa
Chetna Govind, Lancet Laboratories, Durban, South Africa
Elsie Lewis, Steve Biko Pretoria Academic Hospital, Pretoria, South Africa
Warren Lowman, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; and WITS Donald Gordon Medical Centre and Vermaak and Partners Pathologists, Johannesburg, South Africa
Hleziphi Mahlangu, Clinix Health Group, Johannesburg, South Africa
Caroline Maslo, Netcare Hospitals Limited, Johannesburg, South Africa
Angeliki Messina, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; and Netcare Hospitals Limited, Johannesburg,, South Africa
Mervyn Mer, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; and Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa
Kim Pieton, Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa
Sharona Seetharam, Lancet Laboratories, Cape Town, South Africa
Charlotte Sriruttan, National Institute for Communicable Diseases [Centre for Healthcare-Associated Infections, Antimicrobial Resistance and Mycoses], a Division of the National Health Laboratory Service, Johannesburg, South Africa; and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Karin Swart, Netcare Hospitals Limited, Johannesburg, South Africa
Erika van Schalkwyk, National Institute for Communicable Diseases [Centre for Healthcare-Associated Infections, Antimicrobial Resistance and Mycoses], a Division of the National Health Laboratory Service, Johannesburg, South Africa

Abstract

Candida auris has been detected at almost 100 South African hospitals, causing large outbreaks in some facilities, and this pathogen now accounts for approximately 1 in 10 cases of candidaemia. The objective of this guideline is to provide updated, evidence-informed recommendations outlining a best-practice approach to prevent, diagnose and manage C. auris disease in public- and private-sector healthcare settings in South Africa. The 18 practical recommendations cover five focus areas: laboratory identification and antifungal susceptibility testing, surveillance and outbreak response, infection prevention and control, clinical management and antifungal stewardship.

Keywords

Candida auris; Candidaemia; Infection Control; Antifungal Treatment; Diagnosis; Antifungal Stewardship.

Metrics

Total abstract views: 6829
Total article views: 8075

 

Crossref Citations

1. Environmental Clonal Spread of Azole-Resistant Candida parapsilosis with Erg11-Y132F Mutation Causing a Large Candidemia Outbreak in a Brazilian Cancer Referral Center
Danilo Y. Thomaz, João N. de Almeida, Odeli N. E. Sejas, Gilda M. B. Del Negro, Gabrielle O. M. H. Carvalho, Viviane M. F. Gimenes, Maria Emilia B. de Souza, Amir Arastehfar, Carlos H. Camargo, Adriana L. Motta, Flávia Rossi, David S. Perlin, Maristela P. Freire, Edson Abdala, Gil Benard
Journal of Fungi  vol: 7  issue: 4  first page: 259  year: 2021  
doi: 10.3390/jof7040259